Archivo de la etiqueta: obesity

Obesity and cognition.

brain cognition

-Marina Muñoz Cervera-

This article published on 21 August 2012 in the journal Neurology brings us new knowledge about obesity and the cognitive function: Obesity phenotypes in midlife and cognition in early old age
The Whitehall II cohort study

The objetive was to examine the association of body mass index (BMI) and metabolic status with cognitive function and decline.

Methods: A total of 6,401 adults (71.2% men), aged 39–63 years in 1991–1993, provided data on BMI (normal weight 18.5–24.9 kg/m2, overweight 25–29.9 kg/m2; and obese ≥30 kg/m2) and metabolic status (abnormality defined as 2 or more of 1) triglycerides ≥1.69 mmol/L or lipid-lowering drugs, 2) systolic blood pressure ≥130 mm Hg, diastolic blood pressure ≥85 mm Hg, or antihypertensive drugs, 3) glucose ≥5.6 mmol/L or medications for diabetes, and 4) high-density lipoprotein cholesterol <1.04 mmol/L for men and <1.29 mmol/L for women). Four cognitive tests (memory, reasoning, semantic, and phonemic fluency) were administered in 1997–1999, 2002–2004, and 2007–2009, standardized to z scores, and averaged to yield a global score.

They obtained the following results:

Of the participants, 31.0% had metabolic abnormalities, 52.7% were normal weight, 38.2% were overweight, and 9.1% were obese. Among the obese, the global cognitive score at baseline (p = 0.82) and decline (p = 0.19) over 10 years was similar in the metabolically normal and abnormal groups. In the metabolically normal group, the 10-year decline in the global cognitive score was similar (p for trend = 0.36) in the normal weight (−0.40; 95% confidence interval [CI] −0.42 to −0.38), overweight (−0.42; 95% CI −0.45 to −0.39), and obese (−0.42; 95% CI −0.50 to −0.34) groups. However, in the metabolically abnormal group, the decline on the global score was faster among obese (−0.49; 95% CI −0.55 to −0.42) than among normal weight individuals (−0.42; 95% CI −0.50 to −0.34), (p = 0.03).

Conclusions: «In these analyses the fastest cognitive decline was observed in those with both obesity and metabolic abnormality».

Link related:Obesity and metabolic syndrome

Source:

Archana Singh-Manoux, PhD, Sébastien Czernichow, MD, PhD, Alexis Elbaz, MD, PhD, Aline Dugravot, MSc, Séverine Sabia, PhD, Gareth Hagger-Johnson, PhD, Sara Kaffashian, MSc, Marie Zins, MD, PhD, Eric J. Brunner, PhD, Hermann Nabi, PhD and Mika Kivimäki, PhD

Neurology August 21, 2012 vol. 79 no. 8 755-762

http://www.neurology.org/content/79/8/755

Image: http://1.bp.blogspot.com/_wXOhLt8TORw/SwQkePemZkI/AAAAAAAAAJ8/C8CPfQeKZxU/s1600/when.jpeg

Obesity and metabolic syndrome.

metabolic syndrome

– Marina Muñoz Cervera-

Metabolic syndrome is a cluster of conditions — increased blood pressure, a high blood sugar level, excess body fat around the waist or abnormal cholesterol levels — that occur together, increasing your risk of heart disease, stroke and diabetes.

Having metabolic syndrome means you have three or more disorders related to your metabolism at the same time, including:

  • Obesity, with your body fat concentrated around your waist (having an «apple shape»). For a metabolic syndrome diagnosis, obesity is defined by having a waist circumference of 40 inches (102 centimeters or cm) or more for men and 35 inches (89 cm) or more for women, although waist circumference cutoff points can vary by race.
  • Increased blood pressure, meaning a systolic (top number) blood pressure measurement of 130 millimeters of mercury (mm Hg) or more or a diastolic (bottom number) blood pressure measurement of 85 mm Hg or more.
  • High blood sugar level, with a fasting blood glucose test result of 100 milligrams/deciliter (mg/dL), or 5.6 millimoles per liter (mmol/L), or more.
  • High cholesterol, with a level of the blood fat called triglycerides of 150 mg/dL, (1.7 millimoles/liter or mmol/L) or more and a level of high-density lipoprotein (HDL) cholesterol — the «good» cholesterol — of less than 40 mg/dL (1.04 mmol/L) for men or 50 mg/dL (1.3 mmol/L) for women.

Having one component of metabolic syndrome means you’re more likely to have others. And the more components you have, the greater are the risks to your health.

Source: Mayo Clinic Staff. Metabolic Syndrome

http://www.mayoclinic.com/health/metabolic%20syndrome/DS00522/DSECTION=symptoms

Image: http://t2.gstatic.com/images?q=tbn:ANd9GcTC6GVHTA8AF-3GbDdrvlRZUvCqdFE1pNTdLgjIvB2R5kzxt5LDReSCdngp

Report: Link between obesity and inadequated sleep.

«Sleep restriction might lead to a greater propensity to overeat due to increased activation of the brain in response to food stimuli, according to US researchers from Columbia University and St Luke’s-Roosevelt Hospital in New York.»

To read more go to the link: Brain response to food stimuli may explain link between inadequate sleep and obesity

Source: EUFIC European Food Information Council

http://www.eufic.org/page/es/show/latest-science-news/page/LS/fftid/Brain-response-food-stimuli-link-inadequate-sleep-obesity/

Image: http://tecnoculto.com/wp-content/uploads/2010/08/sleep.jpg

Marina Muñoz Cervera